Tennessee became the fifth state to formally permit physician-administered stem cell therapy in 2026.
Statute
HB 2246 / Tenn. Code Ann. § 63-1-101 et seq.
Effective
Effective July 1, 2026
Tennessee's HB 2246 authorizes Tennessee-licensed physicians to administer stem cell and regenerative cellular therapies that are not yet FDA-approved for orthopedic, pain management, and wound-care indications, provided cells are sourced from FDA-registered, accredited establishments and patients sign an informed-consent disclosure. It joins Florida, Texas, Utah, and Wyoming as the fifth US state to provide explicit statutory authority for stem cell practice.
Required Statutory Notice
"THIS NOTICE IS PROVIDED TO YOU UNDER TENNESSEE LAW. This physician administers one or more cellular therapies that have not been approved by the U.S. Food and Drug Administration for the indication discussed. You are encouraged to consult with your primary care provider before undergoing any stem cell therapy."
The requirements below are set by HB 2246 / Tenn. Code Ann. § 63-1-101 et seq.. Compliance is the responsibility of each individual treating physician under their state license.
Statutory compliance does not equal FDA approval. The procedures discussed are investigational and have not been approved by the US Food and Drug Administration.
All procedures discussed are investigational and are not approved by the US Food and Drug Administration. Outcomes vary by patient and are not predictable in advance. Whether a procedure is appropriate is a decision made by the treating physician.
An investigational cellular procedure being explored for adults with knee osteoarthritis. Outcomes vary by patient and are not guaranteed.
Learn more OrthopedicAn investigational cellular procedure being explored for adults with partial-thickness rotator cuff tendon conditions. Outcomes vary and are not guaranteed.
Learn more PainAn investigational cellular procedure being explored for adults with chronic, imaging-documented low back pain. Outcomes vary and are not guaranteed.
Learn more OrthopedicAn investigational cellular procedure being explored for adults with chronic lateral or medial epicondylitis. Outcomes vary by patient.
Learn more OrthopedicAn investigational cellular procedure being explored for adults with hip osteoarthritis. Outcomes vary and are not guaranteed.
Learn moreTennessee has enacted HB 2246 / Tenn. Code Ann. § 63-1-101 et seq., which sets out specific conditions under which a state-licensed physician may practice in this area. The procedures discussed here are investigational and have not been approved by the US Food and Drug Administration.
No. Adults may travel to Tennessee from any US state for an in-person consultation with a network physician. Whether any procedure is appropriate is a clinical decision determined by the treating physician.
Cost depends on the indication, the cell product, and the treating physician. Each physician sets their own pricing and provides a written estimate. Select Stem Cell does not collect medical fees on behalf of physicians.
Yes. Tennessee law requires the treating physician to provide written disclosure of investigational status and obtain informed consent prior to any procedure.
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